Course Description

Principles of environmental and occupational toxicology; dose-response relationship; the mechanisms and fate of chemical interact with biological systems, acute and chronic toxicity which lead to organ toxicities, teratogenicity, mutation, and cancer; properties of widely used hazardous toxicants in environmental, agricultural, and industrial occupations; toxicant biomarkers; inspection, risk assessment

Learning Objectives:

At the end of this course, the student will be able to

1) Explain basic principles of toxicology and dose-response theory

2) Describe absorption, distribution, biotransformation, and excretion process of toxicants

3) Describe reactions and enzymes involved in biotransformation

4) Describe biochemical mechanisms of toxicity

5) Describe basic principles of organ system toxicology

6) Describe basic principles of genetic toxicology and carcinogenesis

7) Describe specific classes of toxicological agents of important in the workplace and community

8) Describe biomarkers of exposure and effect for toxicants

9) Explain risk assessment for toxicants found in the workplace and environmental

10) Develop skill on toxic screening tests